Synthesis of Novel Pyrido[1,2-c]pyrimidine Derivatives with 6-Fluoro-3-(4-piperidynyl)-1,2-benzisoxazole Moiety as Potential SSRI and 5-HT(1A) Receptor Ligands

Two series of novel 4-aryl-2H-pyrido[1,2-c]pyrimidine (6a–i) and 4-aryl-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine (7a–i) derivatives were synthesized. The chemical structures of the new compounds were confirmed by (1)H and (13)C NMR spectroscopy and ESI-HRMS spectrometry. The affinities of all compo...

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Detalles Bibliográficos
Autores principales: Król, Marek, Ślifirski, Grzegorz, Kleps, Jerzy, Ulenberg, Szymon, Belka, Mariusz, Bączek, Tomasz, Siwek, Agata, Stachowicz, Katarzyna, Szewczyk, Bernadeta, Nowak, Gabriel, Duszyńska, Beata, Herold, Franciszek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956643/
https://www.ncbi.nlm.nih.gov/pubmed/33652672
http://dx.doi.org/10.3390/ijms22052329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956643/
https://www.ncbi.nlm.nih.gov/pubmed/33652672
http://dx.doi.org/10.3390/ijms22052329

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