Renal Tubular Epithelial TRPA1 Acts as An Oxidative Stress Sensor to Mediate Ischemia-Reperfusion-Induced Kidney Injury through MAPKs/NF-κB Signaling

Oxidative stress and inflammation play important roles in the pathophysiology of acute kidney injury (AKI). Transient receptor potential ankyrin 1 (TRPA1) is a Ca2+-permeable ion channel that is sensitive to reactive oxygen species (ROS). The role of TRPA1 in AKI remains unclear. In this study, we u...

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Detalles Bibliográficos
Autores principales: Wu, Chung-Kuan, Wu, Chia-Lin, Lee, Tzong-Shyuan, Kou, Yu Ru, Tarng, Der-Cherng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956664/
https://www.ncbi.nlm.nih.gov/pubmed/33669091
http://dx.doi.org/10.3390/ijms22052309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956664/
https://www.ncbi.nlm.nih.gov/pubmed/33669091
http://dx.doi.org/10.3390/ijms22052309

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