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Proteomics Approach of Rapamycin Anti-Tumoral Effect on Primary and Metastatic Canine Mammary Tumor Cells In Vitro

Rapamycin is an antifungal drug with antitumor activity and acts inhibiting the mTOR complex. Due to drug antitumor potential, the aim of this study was to evaluate its effect on a preclinical model of primary mammary gland tumors and their metastases from female dogs. Four cell lines from our cell...

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Detalles Bibliográficos
Autores principales: Lainetti, Patrícia F., Leis-Filho, Antonio F., Kobayashi, Priscila E., de Camargo, Laíza S., Laufer-Amorim, Renee, Fonseca-Alves, Carlos E., Souza, Fabiana F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956669/
https://www.ncbi.nlm.nih.gov/pubmed/33668689
http://dx.doi.org/10.3390/molecules26051213