The CD44high Subpopulation of Multifraction Irradiation-Surviving NSCLC Cells Exhibits Partial EMT-Program Activation and DNA Damage Response Depending on Their p53 Status

Ionizing radiation (IR) is used for patients diagnosed with unresectable non-small cell lung cancer (NSCLC). However, radiotherapy remains largely palliative due to the survival of specific cell subpopulations. In the present study, the sublines of NSCLC cells, A549IR (p53wt) and H1299IR (p53null) s...

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Detalles Bibliográficos
Autores principales: Pustovalova, Margarita, Alhaddad, Lina, Blokhina, Taisia, Smetanina, Nadezhda, Chigasova, Anna, Chuprov-Netochin, Roman, Eremin, Petr, Gilmutdinova, Ilmira, Osipov, Andreyan N., Leonov, Sergey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956695/
https://www.ncbi.nlm.nih.gov/pubmed/33673439
http://dx.doi.org/10.3390/ijms22052369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956695/
https://www.ncbi.nlm.nih.gov/pubmed/33673439
http://dx.doi.org/10.3390/ijms22052369

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