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Metabotropic Glutamate Receptor Blockade Reduces Preservation Damage in Livers from Donors after Cardiac Death

We previously demonstrated that the blockade of mGluR5 by 2-methyl-6(phenylethynyl)pyridine (MPEP) reduces both cold and warm ischemia/reperfusion injury. Here we evaluated whether MPEP reduces the hepatic preservation injury in rat livers from cardiac-death-donors (DCDs). Livers from DCD rats were...

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Detalles Bibliográficos
Autores principales: Di Pasqua, Laura Giuseppina, Berardo, Clarissa, Cagna, Marta, Verta, Roberta, Collotta, Debora, Nicoletti, Ferdinando, Ferrigno, Andrea, Collino, Massimo, Vairetti, Mariapia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956702/
https://www.ncbi.nlm.nih.gov/pubmed/33668105
http://dx.doi.org/10.3390/ijms22052234