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Chemokines Up-Regulated in Epithelial Cells Control Senescence-Associated T Cell Accumulation in Salivary Glands of Aged and Sjögren’s Syndrome Model Mice

Immunosenescence is characterized by age-associated changes in immunological functions. Although age- and autoimmune-related sialadenitis cause dry mouth (xerostomia), the roles of immunosenescence and cellular senescence in the pathogenesis of sialadenitis remain unknown. We demonstrated that acqui...

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Detalles Bibliográficos
Autores principales: Kurosawa, Mie, Shikama, Yosuke, Furukawa, Masae, Arakaki, Rieko, Ishimaru, Naozumi, Matsushita, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956724/
https://www.ncbi.nlm.nih.gov/pubmed/33669065
http://dx.doi.org/10.3390/ijms22052302