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COMP and TSP-4: Functional Roles in Articular Cartilage and Relevance in Osteoarthritis
Osteoarthritis (OA) is a slow-progressing joint disease, leading to the degradation and remodeling of the cartilage extracellular matrix (ECM). The usually quiescent chondrocytes become reactivated and accumulate in cell clusters, become hypertrophic, and intensively produce not only degrading enzym...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956748/ https://www.ncbi.nlm.nih.gov/pubmed/33668140 http://dx.doi.org/10.3390/ijms22052242 |