Sigma-1 Receptor Agonist TS-157 Improves Motor Functional Recovery by Promoting Neurite Outgrowth and pERK in Rats with Focal Cerebral Ischemia

Sigma-1 (σ-1) receptor agonists are considered as potential treatment for stroke. TS-157 is an alkoxyisoxazole-based σ-1 receptor agonist previously discovered in our group. The present study describes TS-157 profile in a battery of tests for cerebral ischemia. Initial evaluation demonstrated the co...

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Detalles Bibliográficos
Autores principales: Shi, Jun-Jie, Jiang, Qi-Hui, Zhang, Tian-Ning, Sun, Hao, Shi, Wen-Wen, Gunosewoyo, Hendra, Yang, Fan, Tang, Jie, Pang, Tao, Yu, Li-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956808/
https://www.ncbi.nlm.nih.gov/pubmed/33668340
http://dx.doi.org/10.3390/molecules26051212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956808/
https://www.ncbi.nlm.nih.gov/pubmed/33668340
http://dx.doi.org/10.3390/molecules26051212

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