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Sigma-1 Receptor Agonist TS-157 Improves Motor Functional Recovery by Promoting Neurite Outgrowth and pERK in Rats with Focal Cerebral Ischemia

Sigma-1 (σ-1) receptor agonists are considered as potential treatment for stroke. TS-157 is an alkoxyisoxazole-based σ-1 receptor agonist previously discovered in our group. The present study describes TS-157 profile in a battery of tests for cerebral ischemia. Initial evaluation demonstrated the co...

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Detalles Bibliográficos
Autores principales:	Shi, Jun-Jie, Jiang, Qi-Hui, Zhang, Tian-Ning, Sun, Hao, Shi, Wen-Wen, Gunosewoyo, Hendra, Yang, Fan, Tang, Jie, Pang, Tao, Yu, Li-Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956808/ https://www.ncbi.nlm.nih.gov/pubmed/33668340 http://dx.doi.org/10.3390/molecules26051212

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