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Mitochondrial Transfer Improves Cardiomyocyte Bioenergetics and Viability in Male Rats Exposed to Pregestational Diabetes

Offspring born to diabetic or obese mothers have a higher lifetime risk of heart disease. Previously, we found that rat offspring exposed to late-gestational diabetes mellitus (LGDM) and maternal high-fat (HF) diet develop mitochondrial dysfunction, impaired cardiomyocyte bioenergetics, and cardiac...

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Detalles Bibliográficos
Autores principales: Louwagie, Eli J., Larsen, Tricia D., Wachal, Angela L., Gandy, Tyler C.T., Baack, Michelle L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956857/
https://www.ncbi.nlm.nih.gov/pubmed/33673574
http://dx.doi.org/10.3390/ijms22052382