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Repurposing Melt Degradation for the Evaluation of Mixed Amorphous-Crystalline Blends
Medicine regulators require the melting points for crystalline drugs, as they are a test for chemical and physical quality. Many drugs, especially salt-forms, suffer concomitant degradation during melting; thus, it would be useful to know if the endotherm associated with melt degradation may be used...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956934/ https://www.ncbi.nlm.nih.gov/pubmed/33718988 http://dx.doi.org/10.1208/s12249-021-01971-6 |