Anthracycline-Induced Cardiotoxicity: Molecular Insights Obtained from Human-Induced Pluripotent Stem Cell–Derived Cardiomyocytes (hiPSC-CMs)

Anthracyclines are a class of chemotherapy drugs that are highly effective for the treatment of human cancers, but their clinical use is limited by associated dose-dependent cardiotoxicity. The precise mechanisms by which individual anthracycline induces cardiotoxicity are not fully understood. Huma...

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Detalles Bibliográficos
Autores principales: Bozza, William P., Takeda, Kazuyo, Alterovitz, Wei-Lun, Chou, Chao-Kai, Shen, Rong-Fong, Zhang, Baolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956936/
https://www.ncbi.nlm.nih.gov/pubmed/33719006
http://dx.doi.org/10.1208/s12248-021-00576-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956936/
https://www.ncbi.nlm.nih.gov/pubmed/33719006
http://dx.doi.org/10.1208/s12248-021-00576-y

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