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Thymic Epithelial Cell-Derived IL-15 and IL-15 Receptor α Chain Foster Local Environment for Type 1 Innate Like T Cell Development

Expression of tissue-restricted antigens (TRAs) in thymic epithelial cells (TECs) ensures negative selection of highly self-reactive T cells to establish central tolerance. Whether some of these TRAs could exert their canonical biological functions to shape thymic environment to regulate T cell deve...

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Detalles Bibliográficos
Autores principales: Tao, Huishan, Li, Lei, Liao, Nan-Shih, Schluns, Kimberly S., Luckhart, Shirley, Sleasman, John W., Zhong, Xiao-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957058/
https://www.ncbi.nlm.nih.gov/pubmed/33732245
http://dx.doi.org/10.3389/fimmu.2021.623280