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Decreased miR-214–3p activates NF-κB pathway and aggravates osteoarthritis progression

BACKGROUND: Osteoarthritis (OA), a disease with whole-joint damage and dysfunction, is the leading cause of disability worldwide. The progressive loss of hyaline cartilage extracellular matrix (ECM) is considered as its hallmark, but its exact pathogenesis needs to be further clarified. MicroRNA(miR...

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Detalles Bibliográficos
Autores principales: Cao, Yumei, Tang, Su'an, Nie, Xiaoyu, Zhou, Zuoqing, Ruan, Guangfeng, Han, Weiyu, Zhu, Zhaohua, Ding, Changhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957119/
https://www.ncbi.nlm.nih.gov/pubmed/33714889
http://dx.doi.org/10.1016/j.ebiom.2021.103283