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Azathioprine antagonizes aberrantly elevated lipid metabolism and induces apoptosis in glioblastoma
Glioblastoma multiforme (GBM) is the most aggressive type of brain tumor with poor survival rate. Temozolomide (TMZ) is used as standard chemotherapy to treat GBM, but a large number of patients either respond poorly and/or develop resistance after long-term use, emphasizing the need to develop pote...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957120/ https://www.ncbi.nlm.nih.gov/pubmed/33748720 http://dx.doi.org/10.1016/j.isci.2021.102238 |