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The DNA damage response network in the treatment of head and neck squamous cell carcinoma

BACKGROUND: We sought to determine whether DNA damage response (DDR)-related aberrations predict therapeutic benefit in cisplatin-treated head and neck squamous cell carcinoma (HNSCC) patients and how DDR pathways are modulated after treatment with olaparib alone or in combination with cisplatin or...

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Detalles Bibliográficos
Autores principales: Psyrri, A., Gkotzamanidou, M., Papaxoinis, G., Krikoni, L., Economopoulou, P., Kotsantis, I., Anastasiou, M., Souliotis, V.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957155/
https://www.ncbi.nlm.nih.gov/pubmed/33714009
http://dx.doi.org/10.1016/j.esmoop.2021.100075