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P62‐positive aggregates are homogenously distributed in the myocardium and associated with the type of mutation in genetic cardiomyopathy

Genetic cardiomyopathy is caused by mutations in various genes. The accumulation of potentially proteotoxic mutant protein aggregates due to insufficient autophagy is a possible mechanism of disease development. The objective of this study was to investigate the distribution in the myocardium of suc...

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Detalles Bibliográficos
Autores principales: van der Klooster, Zoë Joy, Sepehrkhouy, Shahrzad, Dooijes, Dennis, te Rijdt, Wouter P., Schuiringa, Frederique S. A. M., Lingeman, Jolanthe, van Tintelen, Johannes Peter, Harakalova, Magdalena, Goldschmeding, Roel, Suurmeijer, Albert J. H., Asselbergs, Folkert W., Vink, Aryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957157/
https://www.ncbi.nlm.nih.gov/pubmed/33605084
http://dx.doi.org/10.1111/jcmm.16388