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P62‐positive aggregates are homogenously distributed in the myocardium and associated with the type of mutation in genetic cardiomyopathy
Genetic cardiomyopathy is caused by mutations in various genes. The accumulation of potentially proteotoxic mutant protein aggregates due to insufficient autophagy is a possible mechanism of disease development. The objective of this study was to investigate the distribution in the myocardium of suc...
Autores principales: | van der Klooster, Zoë Joy, Sepehrkhouy, Shahrzad, Dooijes, Dennis, te Rijdt, Wouter P., Schuiringa, Frederique S. A. M., Lingeman, Jolanthe, van Tintelen, Johannes Peter, Harakalova, Magdalena, Goldschmeding, Roel, Suurmeijer, Albert J. H., Asselbergs, Folkert W., Vink, Aryan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957157/ https://www.ncbi.nlm.nih.gov/pubmed/33605084 http://dx.doi.org/10.1111/jcmm.16388 |
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