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Mesenchymal stromal cells protect hepatocytes from lipotoxicity through alleviation of endoplasmic reticulum stress by restoring SERCA activity

The aim of this study was to investigate how mesenchymal stromal cells (MSCs) modulate metabolic balance and attenuate hepatic lipotoxicity in the context of non‐alcoholic fatty liver disease (NAFLD). In vivo, male SD rats were fed with high‐fat diet (HFD) to develop NAFLD; then, they were treated t...

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Detalles Bibliográficos
Autores principales: Li, Linzhao, Zeng, Xin, Liu, Zhenzhen, Chen, Xuanming, Li, Lan, Luo, Ruixi, Liu, Xiaohong, Zhang, Jie, Liu, Jingping, Lu, Yanrong, Cheng, Jingqiu, Chen, Younan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957164/
https://www.ncbi.nlm.nih.gov/pubmed/33591626
http://dx.doi.org/10.1111/jcmm.16338