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Inhibition of hepatocyte nuclear factor 1β contributes to cisplatin nephrotoxicity via regulation of nf‐κb pathway

Cisplatin nephrotoxicity has been considered as serious side effect caused by cisplatin‐based chemotherapy. Recent evidence indicates that renal tubular cell apoptosis and inflammation contribute to the progression of cisplatin‐induced acute kidney injury (AKI). Hepatocyte nuclear factor 1β (HNF1β)...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Hao, Jielu, Du, Zijun, Li, Peiyao, Hu, Jinghua, Ruan, Mengna, Li, Shulian, Ma, Yuanfang, Lou, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957194/
https://www.ncbi.nlm.nih.gov/pubmed/33512774
http://dx.doi.org/10.1111/jcmm.16316