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M1 Macrophage exosomes MiR‐21a‐5p aggravates inflammatory bowel disease through decreasing E‐cadherin and subsequent ILC2 activation

Abnormal immune regulation is a key feature of the complex pathogenic mechanism of ulcerative colitis (UC). In particular, macrophages and group 2 innate lymphoid cells (ILC2s) are important components of natural immunity that have been shown to play important roles in the pathogenesis of UC, as wel...

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Detalles Bibliográficos
Autores principales: Lu, Jiaxi, Liu, Deliang, Tan, Yuyong, Deng, Feihong, Li, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957199/
https://www.ncbi.nlm.nih.gov/pubmed/33569850
http://dx.doi.org/10.1111/jcmm.16348