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Scoparone alleviates Ang II‐induced pathological myocardial hypertrophy in mice by inhibiting oxidative stress

Long‐term poorly controlled myocardial hypertrophy often leads to heart failure and sudden death. Activation of ras‐related C3 botulinum toxin substrate 1 (RAC1) by angiotensin II (Ang II) plays a pivotal role in myocardial hypertrophy. Previous studies have demonstrated that scoparone (SCO) has ben...

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Detalles Bibliográficos
Autores principales: Lyu, Linmao, Chen, Jiazheng, Wang, Wei, Yan, Tao, Lin, Jiamao, Gao, Hongmei, Li, Hui, Lv, Ruijuan, Xu, Feng, Fang, Lijun, Chen, Yuguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957216/
https://www.ncbi.nlm.nih.gov/pubmed/33560596
http://dx.doi.org/10.1111/jcmm.16304