Molecular modeling provides insights into the loading of sialic acid‐containing antigens onto CRM(197): the role of chain flexibility in conjugation efficiency and glycoconjugate architecture

Vaccination is the most cost-effective way to control disease caused by encapsulated bacteria; the capsular polysaccharide (CPS) is the primary virulence factor and vaccine target. Neisseria meningitidis (Nm) serogroups B, C, Y and W all contain sialic acid, a common surface feature of human pathoge...

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Detalles Bibliográficos
Autores principales: Kuttel, Michelle M., Berti, Francesco, Ravenscroft, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957279/
https://www.ncbi.nlm.nih.gov/pubmed/33721150
http://dx.doi.org/10.1007/s10719-021-09991-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957279/
https://www.ncbi.nlm.nih.gov/pubmed/33721150
http://dx.doi.org/10.1007/s10719-021-09991-x

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