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Molecular modeling provides insights into the loading of sialic acid‐containing antigens onto CRM(197): the role of chain flexibility in conjugation efficiency and glycoconjugate architecture
Vaccination is the most cost-effective way to control disease caused by encapsulated bacteria; the capsular polysaccharide (CPS) is the primary virulence factor and vaccine target. Neisseria meningitidis (Nm) serogroups B, C, Y and W all contain sialic acid, a common surface feature of human pathoge...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957279/ https://www.ncbi.nlm.nih.gov/pubmed/33721150 http://dx.doi.org/10.1007/s10719-021-09991-x |