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Zonal human hepatocytes are differentially permissive to Plasmodium falciparum malaria parasites

Plasmodium falciparum (Pf) is a major cause of human malaria and is transmitted by infected Anopheles mosquitoes. The initial asymptomatic infection is characterized by parasite invasion of hepatocytes, followed by massive replication generating schizonts with blood‐infective merozoites. Hepatocytes...

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Detalles Bibliográficos
Autores principales: Yang, Annie S P, van Waardenburg, Youri M, van de Vegte‐Bolmer, Marga, van Gemert, Geert‐Jan A, Graumans, Wouter, de Wilt, Johannes H W, Sauerwein, Robert W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957391/
https://www.ncbi.nlm.nih.gov/pubmed/33459428
http://dx.doi.org/10.15252/embj.2020106583