The Novel benzamide Derivative, VKNG-2, Restores the Efficacy of Chemotherapeutic Drugs in Colon Cancer Cell Lines by Inhibiting the ABCG2 Transporter

The overexpression of ATP-binding cassette transporter, ABCG2, plays an important role in mediating multidrug resistance (MDR) in certain types of cancer cells. ABCG2-mediated MDR can significantly attenuate or abrogate the efficacy of anticancer drugs by increasing their efflux from cancer cells. I...

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Detalles Bibliográficos
Autores principales: Narayanan, Silpa, Gujarati, Nehaben A., Wang, Jing-Quan, Wu, Zhuo-Xun, Koya, Jagadish, Cui, Qingbin, Korlipara, Vijaya L., Ashby, Charles R., Chen, Zhe-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957563/
https://www.ncbi.nlm.nih.gov/pubmed/33671108
http://dx.doi.org/10.3390/ijms22052463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957563/
https://www.ncbi.nlm.nih.gov/pubmed/33671108
http://dx.doi.org/10.3390/ijms22052463

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