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Quantitative Proteomics Reveals Changes Induced by TIMP-3 on Cell Membrane Composition and Novel Metalloprotease Substrates

Ectodomain shedding is a key mechanism of several biological processes, including cell-communication. Disintegrin and metalloproteinases (ADAMs), together with the membrane-type matrix metalloproteinases, play a pivotal role in shedding transmembrane proteins. Aberrant shedding is associated to seve...

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Detalles Bibliográficos
Autores principales: Carreca, Anna Paola, Pravatà, Veronica Maria, D’Apolito, Danilo, Bonelli, Simone, Calligaris, Matteo, Monaca, Elisa, Müller, Stephan A., Lichtenthaler, Stefan F., Scilabra, Simone Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957584/
https://www.ncbi.nlm.nih.gov/pubmed/33673623
http://dx.doi.org/10.3390/ijms22052392