Obesity-Activated Lung Stromal Cells Promote Myeloid Lineage Cell Accumulation and Breast Cancer Metastasis

SIMPLE SUMMARY: Obese breast cancer patients have an increased risk for metastasis; however, the mechanisms are not well characterized. Here, we show that obesity promotes rapid mammary tumor growth and enhances metastases in mice. Within the lungs of non-tumor-bearing mice, obesity increased recrui...

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Detalles Bibliográficos
Autores principales: Hillers-Ziemer, Lauren E., Williams, Abbey E., Janquart, Amanda, Grogan, Caitlin, Thompson, Victoria, Sanchez, Adriana, Arendt, Lisa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957630/
https://www.ncbi.nlm.nih.gov/pubmed/33670906
http://dx.doi.org/10.3390/cancers13051005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957630/
https://www.ncbi.nlm.nih.gov/pubmed/33670906
http://dx.doi.org/10.3390/cancers13051005

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