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Obesity-Activated Lung Stromal Cells Promote Myeloid Lineage Cell Accumulation and Breast Cancer Metastasis
SIMPLE SUMMARY: Obese breast cancer patients have an increased risk for metastasis; however, the mechanisms are not well characterized. Here, we show that obesity promotes rapid mammary tumor growth and enhances metastases in mice. Within the lungs of non-tumor-bearing mice, obesity increased recrui...
Autores principales: | Hillers-Ziemer, Lauren E., Williams, Abbey E., Janquart, Amanda, Grogan, Caitlin, Thompson, Victoria, Sanchez, Adriana, Arendt, Lisa M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957630/ https://www.ncbi.nlm.nih.gov/pubmed/33670906 http://dx.doi.org/10.3390/cancers13051005 |
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