Inhibition of Inducible Nitric Oxide Synthase Prevents IL-1β-Induced Mitochondrial Dysfunction in Human Chondrocytes

Interleukin (IL)-1β is an important pro-inflammatory cytokine in the progression of osteoarthritis (OA), which impairs mitochondrial function and induces the production of nitric oxide (NO) in chondrocytes. The aim was to investigate if blockade of NO production prevents IL-1β-induced mitochondrial...

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Detalles Bibliográficos
Autores principales: Eitner, Annett, Müller, Sylvia, König, Christian, Wilharm, Arne, Raab, Rebecca, Hofmann, Gunther O., Kamradt, Thomas, Schaible, Hans-Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957659/
https://www.ncbi.nlm.nih.gov/pubmed/33804447
http://dx.doi.org/10.3390/ijms22052477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957659/
https://www.ncbi.nlm.nih.gov/pubmed/33804447
http://dx.doi.org/10.3390/ijms22052477

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