Cargando…

Inhibition of Inducible Nitric Oxide Synthase Prevents IL-1β-Induced Mitochondrial Dysfunction in Human Chondrocytes

Interleukin (IL)-1β is an important pro-inflammatory cytokine in the progression of osteoarthritis (OA), which impairs mitochondrial function and induces the production of nitric oxide (NO) in chondrocytes. The aim was to investigate if blockade of NO production prevents IL-1β-induced mitochondrial...

Descripción completa

Detalles Bibliográficos
Autores principales:	Eitner, Annett, Müller, Sylvia, König, Christian, Wilharm, Arne, Raab, Rebecca, Hofmann, Gunther O., Kamradt, Thomas, Schaible, Hans-Georg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957659/ https://www.ncbi.nlm.nih.gov/pubmed/33804447 http://dx.doi.org/10.3390/ijms22052477

Ejemplares similares

Osteoarthritis-Induced Metabolic Alterations of Human Hip Chondrocytes
por: Eitner, Annett, et al.
Publicado: (2022)

Mechanisms of Osteoarthritic Pain. Studies in Humans and Experimental Models
por: Eitner, Annett, et al.
Publicado: (2017)

Dynamic compression counteracts IL-1β induced inducible nitric oxide synthase and cyclo-oxygenase-2 expression in chondrocyte/agarose constructs
por: Chowdhury, TT, et al.
Publicado: (2008)

Substance P and Alpha-Calcitonin Gene-Related Peptide Differentially Affect Human Osteoarthritic and Healthy Chondrocytes
por: Stöckl, Sabine, et al.
Publicado: (2021)

The expression and regulation of nitric oxide synthase in human osteoarthritis-affected chondrocytes: evidence for up-regulated neuronal nitric oxide synthase
Publicado: (1995)

Mechanisms of Diesel-Induced Endothelial Nitric Oxide Synthase Dysfunction in Coronary Arterioles
por: Cherng, Tom W., et al.
Publicado: (2011)

Involvement of inducible nitric oxide synthase and mitochondrial dysfunction in the pathogenesis of enterovirus 71 infection
por: Dang, Dejian, et al.
Publicado: (2017)

The potential of substance P to initiate and perpetuate cortical spreading depression (CSD) in rat in vivo
por: Richter, Frank, et al.
Publicado: (2018)

Endothelial nitric oxide synthase deficiency and inducible nitric oxide synthase inhibition in the setting of septic cardiomyopathy
por: Sandt, A Van de, et al.
Publicado: (2009)

Role of Polymorphisms of Inducible Nitric Oxide Synthase and Endothelial Nitric Oxide Synthase in Idiopathic Environmental Intolerances
por: De Luca, Chiara, et al.
Publicado: (2015)

Nitric oxide in liver fibrosis: The role of inducible nitric oxide synthase
por: Iwakiri, Yasuko
Publicado: (2015)

A Comparison of the Effects of Neuronal Nitric Oxide Synthase and Inducible Nitric Oxide Synthase Inhibition on Cartilage Damage
por: Gokay, Nevzat Selim, et al.
Publicado: (2016)

Interleukin-1-induced cyclooxygenase-2 and inducible nitric oxide synthase expression in human OA chondrocytes is associated with histone H3K4 methylation
por: Chabane, N, et al.
Publicado: (2010)

Oxidative stress induces chondrocyte telomere instability and chondrocyte dysfunctions in osteoarthritis
por: Yudoh, K, et al.
Publicado: (2003)

Nitric oxide and inducible nitric oxide synthase levels in EE and NERD patients
por: Nejat PishKenari, Fatemeh, et al.
Publicado: (2022)

Adjuvant Immunotherapy Is Dependent on Inducible Nitric Oxide Synthase
por: Kahn, Daniel A., et al.
Publicado: (2001)

Modulation of inducible nitric oxide synthase expression by sumoylation
por: Akar, Candan A, et al.
Publicado: (2009)

Tranexamic Acid in Hip Hemiarthroplasty Surgery: A Retrospective Analysis of Perioperative Outcome
por: Wilharm, Arne, et al.
Publicado: (2023)

Effects of inducible nitric oxide synthase and neuronal nitric oxide synthase inhibition on methicillin-resistant Staphylococcus aureus sepsis
por: Bansal, Kamna, et al.
Publicado: (2008)

Inducible nitric oxide synthase and guinea-pig ileitis induced by adjuvant
por: Seago, N. D., et al.
Publicado: (1995)

IL‐3 is essential for ICOS‐L stabilization on mast cells, and sustains the IL‐33‐induced RORγt(+) T(reg) generation via enhanced IL‐6 induction
por: Drube, Sebastian, et al.
Publicado: (2021)

Production of Nitric Oxide and Expression of Inducible Nitric Oxide Synthase in Ovarian Cystic Tumors
por: Nomelini, Rosekeila Simões, et al.
Publicado: (2008)

Hypergravity upregulates renal inducible nitric oxide synthase expression and nitric oxide production
por: Yoon, Gun, et al.
Publicado: (2016)

Inducible Nitric Oxide Synthase Polymorphisms and Nitric Oxide Levels in Individuals with Chronic Periodontitis
por: Scarel-Caminaga, Raquel M., et al.
Publicado: (2017)

Enhancement of fracture healing in the rat, modulated by compounds that stimulate inducible nitric oxide synthase: Acceleration of fracture healing via inducible nitric oxide synthase
por: Rajfer, R. A., et al.
Publicado: (2017)

Reactivation of latent leishmaniasis by inhibition of inducible nitric oxide synthase
Publicado: (1996)

Modulation of in vivo alloreactivity by inhibition of inducible nitric oxide synthase
Publicado: (1995)

Inducible Nitric Oxide Synthase Genetic Polymorphism and Risk of Asbestosis
por: Franko, Alenka, et al.
Publicado: (2011)

Characterization of Calmodulin-Free Murine Inducible Nitric-Oxide Synthase
por: Nagpal, Latika, et al.
Publicado: (2015)

Contribution of myeloperoxidase and inducible nitric oxide synthase to pathogenesis of psoriasis
por: Dilek, Nursel, et al.
Publicado: (2016)

Hepatic dysfunction and thrombocytopenia induced by excess sFlt1 in mice lacking endothelial nitric oxide synthase
por: Oe, Yuji, et al.
Publicado: (2018)

Involvement of inducible nitric oxide synthase in radiation-induced vascular endothelial damage
por: Hong, Chang-Won, et al.
Publicado: (2013)

Hsp90β inhibition modulates nitric oxide production and nitric oxide-induced apoptosis in human chondrocytes
por: Calamia, Valentina, et al.
Publicado: (2011)

Expression of inducible nitric oxide synthase and formation of nitric oxide by alveolar macrophages: an interspecies comparison.
por: Jesch, N K, et al.
Publicado: (1997)

Transplantation of adipose-derived stem cells overexpressing inducible nitric oxide synthase ameliorates diabetes mellitus-induced erectile dysfunction in rats
por: Zhang, Yan, et al.
Publicado: (2019)

Octacalcium phosphate crystals directly stimulate expression of inducible nitric oxide synthase through p38 and JNK mitogen-activated protein kinases in articular chondrocytes
por: Ea, Hang-Korng, et al.
Publicado: (2005)

Oleate Prevents Palmitate-Induced Mitochondrial Dysfunction in Chondrocytes
por: Vázquez-Mosquera, Maria Eugenia, et al.
Publicado: (2021)

Gallic Acid Attenuates Angiotensin II-Induced Hypertension and Vascular Dysfunction by Inhibiting the Degradation of Endothelial Nitric Oxide Synthase
por: Yan, Xiao, et al.
Publicado: (2020)

Nitric oxide synthase mediates cerebellar dysfunction in mice exposed to repetitive blast-induced mild traumatic brain injury
por: Logsdon, Aric F., et al.
Publicado: (2020)

Oxidative stress and inflammation contribute to traffic noise-induced vascular and cerebral dysfunction via uncoupling of nitric oxide synthases
por: Daiber, Andreas, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_h7fu0n7cahdgn8f5a7512lqc35