Chloroquine-Induced Accumulation of Autophagosomes and Lipids in the Endothelium

Chloroquine (CQ) is an antimalarial drug known to inhibit autophagy flux by impairing autophagosome–lysosome fusion. We hypothesized that autophagy flux altered by CQ has a considerable influence on the lipid composition of endothelial cells. Thus, we investigated endothelial responses induced by CQ...

Descripción completa

Detalles Bibliográficos
Autores principales: Bik, Ewelina, Mateuszuk, Lukasz, Orleanska, Jagoda, Baranska, Malgorzata, Chlopicki, Stefan, Majzner, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957661/
https://www.ncbi.nlm.nih.gov/pubmed/33673688
http://dx.doi.org/10.3390/ijms22052401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957661/
https://www.ncbi.nlm.nih.gov/pubmed/33673688
http://dx.doi.org/10.3390/ijms22052401

Ejemplares similares