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An Integrated Bioinformatics Study of a Novel Niclosamide Derivative, NSC765689, a Potential GSK3β/β-Catenin/STAT3/CD44 Suppressor with Anti-Glioblastoma Properties

Despite management efforts with standard surgery, radiation, and chemotherapy, glioblastoma multiform (GBM) remains resistant to treatment, which leads to tumor recurrence due to glioma stem cells (GSCs) and therapy resistance. In this study, we used random computer-based prediction and target ident...

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Detalles Bibliográficos
Autores principales: Mokgautsi, Ntlotlang, Wen, Ya-Ting, Lawal, Bashir, Khedkar, Harshita, Sumitra, Maryam Rachmawati, Wu, Alexander T. H., Huang, Hsu-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957701/
https://www.ncbi.nlm.nih.gov/pubmed/33671112
http://dx.doi.org/10.3390/ijms22052464