Silencing DNA Polymerase β Induces Aneuploidy as a Biomarker of Poor Prognosis in Oral Squamous Cell Cancer

Most patients with oral squamous cell cancer (OSCC) have a locally advanced stage at diagnosis. The treatment strategies are diverse, including surgery, radiotherapy and chemotherapy. Despite multimodality treatment, the response rate is unsatisfactory. DNA repair and genetic instability are highly...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Hui-Ching, Chan, Leong-Perng, Wu, Chun-Chieh, Chang, Shu-Jyuan, Moi, Sin-Hua, Luo, Chi-Wen, Pan, Mei-Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957714/
https://www.ncbi.nlm.nih.gov/pubmed/33673690
http://dx.doi.org/10.3390/ijms22052402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957714/
https://www.ncbi.nlm.nih.gov/pubmed/33673690
http://dx.doi.org/10.3390/ijms22052402

Ejemplares similares