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Silencing DNA Polymerase β Induces Aneuploidy as a Biomarker of Poor Prognosis in Oral Squamous Cell Cancer

Most patients with oral squamous cell cancer (OSCC) have a locally advanced stage at diagnosis. The treatment strategies are diverse, including surgery, radiotherapy and chemotherapy. Despite multimodality treatment, the response rate is unsatisfactory. DNA repair and genetic instability are highly...

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Detalles Bibliográficos
Autores principales: Wang, Hui-Ching, Chan, Leong-Perng, Wu, Chun-Chieh, Chang, Shu-Jyuan, Moi, Sin-Hua, Luo, Chi-Wen, Pan, Mei-Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957714/
https://www.ncbi.nlm.nih.gov/pubmed/33673690
http://dx.doi.org/10.3390/ijms22052402

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