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Silencing DNA Polymerase β Induces Aneuploidy as a Biomarker of Poor Prognosis in Oral Squamous Cell Cancer
Most patients with oral squamous cell cancer (OSCC) have a locally advanced stage at diagnosis. The treatment strategies are diverse, including surgery, radiotherapy and chemotherapy. Despite multimodality treatment, the response rate is unsatisfactory. DNA repair and genetic instability are highly...
Autores principales: | Wang, Hui-Ching, Chan, Leong-Perng, Wu, Chun-Chieh, Chang, Shu-Jyuan, Moi, Sin-Hua, Luo, Chi-Wen, Pan, Mei-Ren |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957714/ https://www.ncbi.nlm.nih.gov/pubmed/33673690 http://dx.doi.org/10.3390/ijms22052402 |
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