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TRAF4/6 Is Needed for CD44 Cleavage and Migration via RAC1 Activation

SIMPLE SUMMARY: Tumor cells receive signals from the surrounding extracellular matrix that affect their growth and survival. An important component of the extracellular matrix is the large polysaccharide hyaluronan, which binds and activates certain receptors at the cell surface, including CD44. Act...

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Detalles Bibliográficos
Autores principales: Kolliopoulos, Constantinos, Chatzopoulos, Athanasios, Skandalis, Spyros S., Heldin, Carl-Henrik, Heldin, Paraskevi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957764/
https://www.ncbi.nlm.nih.gov/pubmed/33804427
http://dx.doi.org/10.3390/cancers13051021