The ALS-Associated FUS (P525L) Variant Does Not Directly Interfere with Microtubule-Dependent Kinesin-1 Motility

Deficient intracellular transport is a common pathological hallmark of many neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). Mutations in the fused-in-sarcoma (FUS) gene are one of the most common genetic causes for familial ALS. Motor neurons carrying a mutation in the nuc...

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Detalles Bibliográficos
Autores principales: Seifert, Anne, Drechsler, Hauke, Japtok, Julia, Korten, Till, Diez, Stefan, Hermann, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957795/
https://www.ncbi.nlm.nih.gov/pubmed/33670886
http://dx.doi.org/10.3390/ijms22052422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957795/
https://www.ncbi.nlm.nih.gov/pubmed/33670886
http://dx.doi.org/10.3390/ijms22052422

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