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CENPE Inhibition Leads to Mitotic Catastrophe and DNA Damage in Medulloblastoma Cells

SIMPLE SUMMARY: Medulloblastoma (MB) is the most frequent brain tumor in children. The standard treatment consists in surgery, followed by radiotherapy and chemotherapy. These therapies are only partially effective, since many patients still die and those who survive suffer from neurological and end...

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Detalles Bibliográficos
Autores principales: Iegiani, Giorgia, Gai, Marta, Di Cunto, Ferdinando, Pallavicini, Gianmarco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957796/
https://www.ncbi.nlm.nih.gov/pubmed/33804489
http://dx.doi.org/10.3390/cancers13051028