Effects of the Novel PFKFB3 Inhibitor KAN0438757 on Colorectal Cancer Cells and Its Systemic Toxicity Evaluation In Vivo

SIMPLE SUMMARY: Glycolysis is one of the hallmarks of cancer. Therefore, the development of novel therapeutical strategies for colorectal cancer targeting glycolysis may improve treatment responses. PFKFB3 expression has been directly associated with enhanced glycolysis, not only in cancer cells but...

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Detalles Bibliográficos
Autores principales: De Oliveira, Tiago, Goldhardt, Tina, Edelmann, Marcus, Rogge, Torben, Rauch, Karsten, Kyuchukov, Nikola Dobrinov, Menck, Kerstin, Bleckmann, Annalen, Kalucka, Joanna, Khan, Shawez, Gaedcke, Jochen, Haubrock, Martin, Beissbarth, Tim, Bohnenberger, Hanibal, Planque, Mélanie, Fendt, Sarah-Maria, Ackermann, Lutz, Ghadimi, Michael, Conradi, Lena-Christin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957803/
https://www.ncbi.nlm.nih.gov/pubmed/33671096
http://dx.doi.org/10.3390/cancers13051011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957803/
https://www.ncbi.nlm.nih.gov/pubmed/33671096
http://dx.doi.org/10.3390/cancers13051011

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