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Identification of Cyclophilin A as a Potential Anticancer Target of Novel Nargenicin A1 Analog in AGS Gastric Cancer Cells

We recently discovered a novel nargenicin A1 analog, 23-demethyl 8,13-deoxynargenicin (compound 9), with potential anti-cancer and anti-angiogenic activities against human gastric adenocarcinoma (AGS) cells. To identify the key molecular targets of compound 9, that are responsible for its biological...

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Detalles Bibliográficos
Autores principales: Han, Jang Mi, Sohng, Jae Kyung, Lee, Woo-Haeng, Oh, Tae-Jin, Jung, Hye Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957809/
https://www.ncbi.nlm.nih.gov/pubmed/33804393
http://dx.doi.org/10.3390/ijms22052473