Gain-of-function p53 protein transferred via small extracellular vesicles promotes conversion of fibroblasts to a cancer-associated phenotype

Tumor and stromal interactions consist of reciprocal signaling through cytokines, growth factors, direct cell-cell interactions, and extracellular vesicles (EVs). Small EVs (≤200 nm) have been considered critical messengers of cellular communication during tumor development. Here, we demonstrate tha...

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Detalles Bibliográficos
Autores principales: Ma, Shaolin, McGuire, Michael H., Mangala, Lingegowda S., Lee, Sanghoon, Stur, Elaine, Hu, Wen, Bayraktar, Emine, Villar-Prados, Alejandro, Ivan, Cristina, Wu, Sherry Y., Yokoi, Akira, Dasari, Santosh K., Jennings, Nicholas B., Liu, Jinsong, Lopez-Berestein, Gabriel, Ram, Prahlad, Sood, Anil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957825/
https://www.ncbi.nlm.nih.gov/pubmed/33567287
http://dx.doi.org/10.1016/j.celrep.2021.108726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957825/
https://www.ncbi.nlm.nih.gov/pubmed/33567287
http://dx.doi.org/10.1016/j.celrep.2021.108726

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