How Hydrogen Bonding Amplifies Isomeric Differences in Pyridones toward Strong Changes in Acidity and Tautomerism

[Image: see text] Steric hindrance of hydration and hydrogen bond enhancement by localized charges have been identified as key factors for the massive chemical differences between the hydroxypyridine/pyridone isomers in aqueous solution. While all isomers occur mainly in the hydroxypyridine form in...

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Detalles Bibliográficos
Autores principales: Büchner, Robby, Fondell, Mattis, Mascarenhas, Eric J., Pietzsch, Annette, Vaz da Cruz, Vinícius, Föhlisch, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957858/
https://www.ncbi.nlm.nih.gov/pubmed/33562959
http://dx.doi.org/10.1021/acs.jpcb.0c10873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957858/
https://www.ncbi.nlm.nih.gov/pubmed/33562959
http://dx.doi.org/10.1021/acs.jpcb.0c10873

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