The Selectivity for Tumor Cells of Nuclear-Directed Cytotoxic RNases Is Mediated by the Nuclear/Cytoplasmic Distribution of p27(KIP1)

Although single targeted anti-cancer drugs are envisaged as safer treatments because they do not affect normal cells, cancer is a very complex disease to be eradicated with a single targeted drug. Alternatively, multi-targeted drugs may be more effective and the tumor cells may be less prone to deve...

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Detalles Bibliográficos
Autores principales: García-Galindo, Glòria, Castro, Jessica, Matés, Jesús, Bravo, Marlon, Ribó, Marc, Vilanova, Maria, Benito, Antoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957890/
https://www.ncbi.nlm.nih.gov/pubmed/33801209
http://dx.doi.org/10.3390/molecules26051319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957890/
https://www.ncbi.nlm.nih.gov/pubmed/33801209
http://dx.doi.org/10.3390/molecules26051319

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