A Critical Perspective on 3D Liver Models for Drug Metabolism and Toxicology Studies

The poor predictability of human liver toxicity is still causing high attrition rates of drug candidates in the pharmaceutical industry at the non-clinical, clinical, and post-marketing authorization stages. This is in part caused by animal models that fail to predict various human adverse drug reac...

Descripción completa

Detalles Bibliográficos
Autores principales: Serras, Ana S., Rodrigues, Joana S., Cipriano, Madalena, Rodrigues, Armanda V., Oliveira, Nuno G., Miranda, Joana P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957963/
https://www.ncbi.nlm.nih.gov/pubmed/33732695
http://dx.doi.org/10.3389/fcell.2021.626805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957963/
https://www.ncbi.nlm.nih.gov/pubmed/33732695
http://dx.doi.org/10.3389/fcell.2021.626805

Ejemplares similares