Cargando…
A Critical Perspective on 3D Liver Models for Drug Metabolism and Toxicology Studies
The poor predictability of human liver toxicity is still causing high attrition rates of drug candidates in the pharmaceutical industry at the non-clinical, clinical, and post-marketing authorization stages. This is in part caused by animal models that fail to predict various human adverse drug reac...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957963/ https://www.ncbi.nlm.nih.gov/pubmed/33732695 http://dx.doi.org/10.3389/fcell.2021.626805 |