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The m6A methyltransferase METTL14 inhibits the proliferation, migration, and invasion of gastric cancer by regulating the PI3K/AKT/mTOR signaling pathway

BACKGROUND: N6‐methyladenosine (m6A) modification may participate in the regulation of occurrence and development of tumors. However, the m6A level and the potential regulatory mechanism of m6A in gastric cancer (GC) remain uncertain. METHODS: RNA m6A quantification assay was conducted to detect the...

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Detalles Bibliográficos
Autores principales: Liu, Xin, Xiao, Mingyang, Zhang, Liang, Li, Liuli, Zhu, Guolian, Shen, Erdong, Lv, Mingyue, Lu, Xiaobo, Sun, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957981/
https://www.ncbi.nlm.nih.gov/pubmed/33314339
http://dx.doi.org/10.1002/jcla.23655