Structural insights into α-synuclein monomer–fibril interactions

Protein aggregation into amyloid fibrils is associated with multiple neurodegenerative diseases, including Parkinson’s disease. Kinetic data and biophysical characterization have shown that the secondary nucleation pathway highly accelerates aggregation via the absorption of monomeric protein on the...

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Detalles Bibliográficos
Autores principales: Kumari, Pratibha, Ghosh, Dhiman, Vanas, Agathe, Fleischmann, Yanick, Wiegand, Thomas, Jeschke, Gunnar, Riek, Roland, Eichmann, Cédric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7958257/
https://www.ncbi.nlm.nih.gov/pubmed/33649211
http://dx.doi.org/10.1073/pnas.2012171118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7958257/
https://www.ncbi.nlm.nih.gov/pubmed/33649211
http://dx.doi.org/10.1073/pnas.2012171118

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