Genomic Space of MGMT in Human Glioma Revisited: Novel Motifs, Regulatory RNAs, NRF1, 2, and CTCF Involvement in Gene Expression

Background: The molecular regulation of increased MGMT expression in human brain tumors, the associated regulatory elements, and linkages of these to its epigenetic silencing are not understood. Because the heightened expression or non-expression of MGMT plays a pivotal role in glioma therapeutics,...

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Detalles Bibliográficos
Autores principales: Ibrahim Al-Obaide, Mohammed A., Arutla, Viswanath, Bacolod, Manny D., Wang, Wei, Zhang, Ruiwen, Srivenugopal, Kalkunte S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7958331/
https://www.ncbi.nlm.nih.gov/pubmed/33801310
http://dx.doi.org/10.3390/ijms22052492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7958331/
https://www.ncbi.nlm.nih.gov/pubmed/33801310
http://dx.doi.org/10.3390/ijms22052492

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