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Hepatitis B virus X protein promotes vimentin expression via LIM and SH3 domain protein 1 to facilitate epithelial-mesenchymal transition and hepatocarcinogenesis

BACKGROUND: Hepatitis B virus (HBV) X protein (HBX) has been reported to be responsible for the epithelial-mesenchymal transition (EMT) in HBV-related hepatocellular carcinoma (HCC). Vimentin is an EMT-related molecular marker. However, the importance of vimentin in the pathogenesis of HCC mediated...

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Detalles Bibliográficos
Autores principales: You, Hongjuan, Yuan, Dongchen, Bi, Yanwei, Zhang, Ning, Li, Qi, Tu, Tao, Wei, Xiao, Lian, Qi, Yu, Tong, Kong, Delong, Yang, Xiaoying, Liu, Xiangye, Liu, Xiaomei, Kong, Fanyun, Zheng, Kuiyang, Tang, Renxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7958410/
https://www.ncbi.nlm.nih.gov/pubmed/33722250
http://dx.doi.org/10.1186/s12964-021-00714-1