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Ligand effects on phase separation of multivalent macromolecules

Biomolecular condensates enable spatial and temporal control over cellular processes by concentrating biomolecules into nonstoichiometric assemblies. Many condensates form via reversible phase transitions of condensate-specific multivalent macromolecules known as scaffolds. Phase transitions of scaf...

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Detalles Bibliográficos
Autores principales: Ruff, Kiersten M., Dar, Furqan, Pappu, Rohit V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7958451/
https://www.ncbi.nlm.nih.gov/pubmed/33653957
http://dx.doi.org/10.1073/pnas.2017184118